When making b&w prints on Entrada Natural for example using an Epson printer (3880, 3800) and printing from Lightroom is your recommendation to use the Entrada color icc.profile and make the print using the color settings or do you recommend turning off the profile, letting the printer manage and use the Advanced Black & White settings on the Epson?

When making black and white prints, I suggest selecting 'printer manages colors' and choosing the black and white mode in your printer. For Epson photo printers, this is 'Advanced Black and White'. For Canon photo printers, check the box for 'Black and White Photo Print'. Using the print driver B&W setting generally gives you a more neutral tone in your prints, and better overall tonality than printing a B&W image with a color profile.

Also, for Epson printers there is a third-party software program called Quad Tone RIP for printing black and white images, which allows you to create B&W specific profiles and adjust other printing parameters.